Paul Herman

Paul Herman

Paul Herman

Professor, Dept. of Molecular Genetics

herman.81@osu.edu

614-292-4466

842 Riffe Bldg.
496 W. 12th Ave.
Columbus, OH 43210

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Areas of Expertise

  • Molecular Genetics
  • Cell Signaling
  • Protein Homeostasis
  • Cellular Compartmentalization

Keywords: Growth control; Ras proteins; Cancer; cAMP-dependent protein kinase (PKA); Protein phosphorylation; Signal transduction; Stationary phase; P bodies; Ribonucleoprotein (RNP) complexes.

RESEARCH INTERESTS: The regulation of quiescence

Our lab is interested in understanding the mechanisms controlling eukaryotic cell growth and proliferation. Our primary focus has been on the G₀-like resting states that cells enter when conditions are not conducive to continued growth. The transitions between active division and these periods of quiescence are known to be key points of proliferative control. We are interested in characterizing the signaling pathways that control these transitions and the processes required for the maintenance of cell viability in the absence of division. The long-term goals of this work are to develop a more complete understanding of the general control of cell proliferation and to identify novel targets for the treatment of proliferative disorders, including human cancers. More information about our research can be found by visiting our lab web site (see below for link).

 

Please see the Herman Lab Website for more information